Takayuki Okamoto, Ph.D.

Takayuki Okamoto is affiliated with the Center for Frontier Medical Engineering, Chiba University. His research focuses on biomedical imaging and image analysis for visualizing and quantifying the three-dimensional structures of biological tissues, mainly based on micro-X-ray CT systems and optical coherence tomography (OCT).

Latest News

  • 2026-10-27

    We will give five oral presentations and one invited talk at Optics & Photonics Japan 2026, to be held in Hamamatsu, Shizuoka, Japan, from Wednesday, December 16 to Friday, December 18, 2026.

    • Investigation of a Variable-Zoom Micro-CT Reconstruction Method Using Unsupervised Deep Learning [Results of joint research with the National Institute of Advanced Industrial Science and Technology (AIST)]
    • Investigation of a Missing-Data Interpolation Method for Sliding-Window Acquisition in X-ray Phase-Contrast Micro-CT
    • Wave-Optics Simulation of Single-Shot X-ray Phase-Contrast Imaging Using a Single Diffraction Grating
    • Evaluation of Layer Discrimination in Red Dichromatic Imaging (RDI) Using RGB Pixel Values Estimated by Optical Simulation [Results of joint research with the National Cancer Center Japan]
    • Hemodynamic Analysis of Rat Skin Flaps with Vascular Occlusion Using a Hyperspectral Camera
    • Choroidal Structural Analysis in Three-Dimensional OCT Images and Its Application to Treatment Support [Invited Talk]
  • 2026-10-21

    We will present the results of our joint research with the National Institute of Advanced Industrial Science and Technology (AIST) at the 2026 IEEE NSS MIC RTSD, to be held in Granada, Spain, from November 7 to 14, 2026.

    • Unsupervised micro-CT reconstruction from limited-angle and truncated data in cone-beam geometry (link)
  • 2026-10-05

    I attended the 35th Annual Meeting of the Japan Society for Bioimaging, held in Kyoto, Japan. A first-year doctoral student under my supervision received a Scholarship Award.

  • 2026-09-30

    I hosted a site visit for members of the JST ACT-X program.

  • 2026-09-28

    We will give three presentations at The 35th Annual Meeting of the Bioimaging Society, to be held in Kyoto, Japan, on October 4–5, 2026.

    • Morphological variation analysis of parametrically controlled 3D data using a variational autoencoder
    • Laboratory-based X-ray phase-contrast imaging of vertebrate model organisms using a Talbot–Lau interferometry
    • Temporal quantitative assessment of microcirculatory tortuosity associated with flap necrosis
  • 2026-09-17

    I gave an invited lecture at the 116th Regular Meeting of the JSPE Expert Committee for Convergence Engineering.

  • 2026-09-17

    My research project has been selected for FY2026 PRESTO (SAKIGAKE), Strategic Basic Research Programs of the Japan Science and Technology Agency (JST).

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Micro X-ray CT

Using micro-X-ray CT as a core technology, we are developing methods to visualize and quantify the fine internal morphology of biological tissues with high precision in a non-destructive manner.

  • Development of phase-contrast micro-X-ray CT systems
  • Investigation of image reconstruction methods using sparse projection data
  • Establishment of fundamental technologies for morphological analysis and quantification of three-dimensional images
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OCT

We are developing automated analysis frameworks to reliably extract tissue structures and vascular information from three-dimensional images acquired using optical coherence tomography (OCT).

  • Segmentation and quantitative analysis of three-dimensional choroidal structures
  • Quantitative evaluation of tissue structures in OCT images of diseased eyes
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